INVERSE DATA-DRIVEN MODELING AND MULTIOMICS ANALYSIS REVEALS PHGDH AS A METABOLIC CHECKPOINT OF MACROPHAGE POLARIZATION AND PROLIFERATION

Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation

Summary: Mechanistic or mammalian target of rapamycin complex 1 (mTORC1) is an important regulator of effector functions, proliferation, and cellular metabolism in macrophages.The biochemical processes that are controlled by mTORC1 are still being defined.Here, we demonstrate that integrative multiomics in conjunction with a data-driven inverse mod

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Discrimination of haploids and doubled haploids/diploids in indica rice: correlation of morphological indicators with molecular markers

To obtain immediate homozygosity by androgenesis, the doubled haploid method is often used.As a result, a mapping population was created utilizing rice (Oryza sativa L.) cvs.Mahulata and IR 20 as parents in order to find QTLs/genes for drought tolerance at the vegetative stage.The effectiveness of the doubled haploids (DHs) approach, on the other h

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Drone Brood Homogenate as Natural Remedy for Treating Health Care Problem: A Scientific and Practical Approach

Drone brood homogenate is a little-known bee product used in folk medicine to treat various health problems.It VEGI SOUP MIX is a very nutritious milky substance with high content of nutrients: proteins, lipids, fatty acids, carbohydrates, vitamins (A, B, E and D), and minerals.Moreover, when collected on early stage of larvae development, it is, m

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Biodiversity of genus Orius (Hemiptera: Anthocoridae) in various climate regions and seasons of Kohgiloyeh and Boyerahmad province and evaluation of agro-ecosystem effects on their biodiversity

The members of genus Orius are known as natural enemies of many of plant pests in the world.We studied the fauna and biodiversity of the family Anthocoridae bugs in different environmental conditions of Kohgiloyeh and Boyrahmad province of Iran.Sampling took place in three climates and from three ecosystems (gardens, farms and virgin uncultivated l

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